Search results for "oxidant stre"

showing 8 items of 8 documents

C-reactive protein and intercellular adhesion molecule-1 are stronger predictors of oxidant stress than blood pressure in established hypertension

2007

Oxidant stress is implicated in the pathogenesis of atherosclerosis in cardiovascular diseases. Our aim was to test oxidative stress, as 8-iso-prostaglandin F2alpha (8-iso-PGF2alpha), and its relationship with inflammation markers C-reactive protein (CRP) and tumour necrosis factor-alpha (TNFalpha), and endothelial activation assayed as soluble intercellular adhesion molecule (ICAM)-1 and vascular cell adhesion molecule (VCAM)-1 in essential hypertension.In 216 essential hypertensive patients and 55 healthy control individuals, plasma levels of high-sensitivity CRP and TNFalpha, 8-iso-PGF2alpha, ICAM-1 and VCAM-1 were measured in basal conditions. Moreover, basal and 24-h ambulatory blood p…

Adultmedicine.medical_specialtyPhysiologyIntercellular Adhesion Molecule-1Vascular Cell Adhesion Molecule-1InflammationBlood Pressuremedicine.disease_causeDinoprostC-reactive protein oxidant stress hypertensionPathogenesisPredictive Value of TestsInternal medicineInternal MedicinemedicineHumansEndothelial dysfunctionInflammationbiologybusiness.industryTumor Necrosis Factor-alphaC-reactive proteinBlood Pressure Monitoring AmbulatoryMiddle Agedmedicine.diseaseIntercellular Adhesion Molecule-1Oxidative StressBlood pressureEndocrinologyC-Reactive ProteinCase-Control StudiesImmunologyHypertensionbiology.proteinTumor necrosis factor alphamedicine.symptomCardiology and Cardiovascular MedicinebusinessOxidative stressBiomarkers
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Relation of oxidant stress with endothelial activation in hemodialysis.

2006

Introduction and Aims: Enhanced oxidative stress may be implicated in the pathogenesis of atherosclerosis in hemodialysed patients (HDs). We hypothesized that in hypertensive HDs oxidative stress should be elevated and associated to endothelial activation, and inflammation. Methods:We examined oxidative stress, as measured by 8-ISO-PGF2alpha, endothelial activation by measuring endothelin-1 (ET-1) and adhesion molecules ICAM-1 and VCAM-1, and the biomarker of acute-phase inflammation CRP. In 52 mild HDs and in 50 healthy controls (Cs) we analysed, in the interdialytic day, plasma levels of 8-ISO-PGF2alpha, ET-1, ICAM-1 and VCAM-1, and high sensitivity CRP. Results: The comparison between Cs…

Atherosclerosis.CKDoxidant streEndotheliumESRD
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C-reactive protein and ICAM-1 are stronger predictors of oxidant stress than blood pressure in established hypertension

2006

C-reactive protein ICAM-1 oxidant stress hypertension
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Oxidant stress and endothelial activation in hypertensive patients with and without left ventricular hypertrophy

2006

Oxidant stress endothelial activation hypertension left ventricular hypertrophy
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Oxidant stress inversely relates to renal function in hypertension

2007

Oxidant stress renal function hypertension
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Oxidant stress is inversely related to renal function in hypertension.

2007

Oxidant stress renal function hypertension
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CD40 ligation protects bronchial epithelium against oxidant-induced caspase-independent cell death.

2006

KEYWORDS CLASSIFICATION: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide;Antigens,CD40;Apoptosis;Bronchi;cytology;Caspases;Cell Cycle;Cell Death;Cell Line,Transformed;Cell Survival;Cell Transformation,Viral;Cytoprotection;drug effects;Epithelial Cells;Humans;Italy;mechanisms of carcinogenesis;metabolism;Oxidants;pharmacology;physiology;Research;Simian virus 40;toxicity;Transcription Factor AP-1. CD40 and its ligand regulate pleiotropic biological responses, including cell proliferation, differentiation, and apoptosis. In many inflammatory lung diseases, tissue damage by environmental or endogenous oxidants plays a major role in disease pathogenesis. As the epithelial barrier is a major t…

Pulmonary and Respiratory MedicineNF-BProgrammed cell deathCell SurvivalClinical Biochemistry78-Dihydro-78-dihydroxybenzo(a)pyrene 910-oxideApoptosisBronchiSimian virus 40Inhibitor of apoptosisAntigens CD40CD40HumansCD40 AntigensMolecular BiologyMitosisCaspaseActivator protein–1Cell Line Transformedoxidant stressbiologyCell DeathCell growthCell CycleEpithelial CellsCell BiologyCell cycleCell Transformation ViralOxidantsapoptosiCell biologyTranscription Factor AP-1activator protein–1ApoptosisCytoprotectionCaspasesbiology.proteinNF- BApoptosis-inducing factorOxidant stress
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Relationship of oxidant stress with endothelial activation in hemodialysed hypertensive patients.

2006

oxidant stress endothelial activation hemodialysis hypertension
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